Km | Vmax | n | CLint | |
---|---|---|---|---|
μM | nmol/min/mg | ml/min/mg | ||
Male | 29.2 ± 10.6 | 0.68 ± 0.12 | 1.34 ± 0.26 | 0.023 |
Female | 26.5 ± 3.8 | 1.64 ± 0.11 | 1.30 ± 0.10 | 0.062 |
The kinetic parameters Km, Vmax, and n (mean ± calculated S.D.) were calculated from data shown in Fig. 4 according to eq. 1. The CLintwas estimated by dividing Vmax byKm.
CLint, intrinsic clearance.