Effect of increasing equilibrium time on the binding of saquinavir (1 μg/ml) to human plasma
| Time | Percentage of Unbound | n |
|---|---|---|
| h | ||
| 2 | 0.84 ± 0.38 | 3 |
| 5 | 0.93 ± 0.32 | 3 |
| 8 | 1.30 ± 0.36 | 3 |
| 18 | 2.52 ± 0.66 | 5 |
| 24 | 2.3 | 2 |
| 28 | 2.63 ± 0.83 | 3 |
Data are expressed as the mean ± S.D.