Table 3

Mutant HFE genotypes in patients with hemochromatosis

Author and ReferenceNumber of patientsGenotype of Affected Individuals
Homozygotes 845A (C282Y)Compound Heterozygotes 845A (C282Y)/187G (H63D)Homozygotes 187G (H63D)Heterozygotes for 845A(C282Y)Heterozygotes for 187G(H63D)
%
Feder (US) (Feder et al., 1996)17883.24.50.60.65.1
Beutler (US) (Beutler et al., 1996)14782.35.41.41.42.7
Jouanolle (France) (Jouanolle et al., 1996)6590.84.61.503.1
Robson (UK) (Robson et al., 1997)11591.32.60.90.90
Adams (Canada) (Adams et al., 1997)7491.9002.70
Borot (France) (Borot et al., 1997)9472.34.32.14.38.5
Carella (Italy) (Carella et al., 1997)7564.06.61.32.74.0
Cardosa (Sweden) (Cardoso et al., 1998)8792.03.51.11.11.1
Ryan (Ireland) (Ryan et al., 1998)7889.73.802.6