Brush-border disaccharidases and their deficiencies
| Di- and Polysaccharide | Enzyme | Gene Locus1-a | Deficiencies |
|---|---|---|---|
| Lactose | Lactase | LCT | Congenital alactasia Lactase nonpersistence |
| Sucrose Maltose Isomaltose | Sucrase-isomaltase | SI | Congenital sucrase deficiency |
| Maltose | Maltase-glucoamylase | MGAM | Congenital maltase—glucoamylase deficiency |
| Terminal alpha 1-4 linkages on polysaccharide | |||
| Trehalose | Trehalase | TREH | Trehalase deficiency |
↵1-a For official gene symbol seehttp://www.gene.ucl.ac.uk/cgi-bin/nomenclature/searchgenes.pl for Online Mendelian Inheritance in Man (OMIM) and other literature and sequence links.