Table 5

Point mutations of human FMO3 associated with fish malodor syndrome

PositionMutation
61Asn → Ser5-a
82Met → Thr5-a
153Pro → Lev5-a
158Glu → Lys
180Gly → Val
257Val → Met
305Glu →X 5-a
434Met → Iso5-a
492Arg → Trp5-a
661Met → Iso5-a
  • 5-a  Inactivates FMO3.