Source | Epirubicin Glucuronide |
---|---|
pmol/min/mg | |
Normal livers | 138 ± 37 |
CN-I n. 1 | 144 ± 6 |
CN-I n. 2 | 104 ± 6 |
UGT2B7 | 63 ± 4 |
UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A9, UGT2B15 | N.D. |
Values are expressed as the mean ± S.D. of a single experiment performed in triplicate. Epirubicin glucuronidation in normal liver microsomes is the mean ± S.D. of 47 individuals
N.D., not detectable.