Oral bioavailability: | 55% |
Total body plasma clearance: | 12 ± 2 ml/min/kg of body weight |
(840 ml/70 kg of bodyweight) | |
Renal clearance: | 2 ml/min/kg of bodyweight |
140 ml/70 kg of bodyweight | |
Plasma protein binding: | 20% |
Volume of distribution: | 2.6 l/kg |
25.6 μmol of the drug was administered orally to 10 healthy volunteers.