Metabolite profiles of AG7088 in hepatic microsomes from five animal species and humans
| Species | AG7088 | M1 + M2 | M3 | M4 | M5 | M6 |
|---|---|---|---|---|---|---|
| Mouse | 0 | + | 0 | +++ ++ | ++ | ++ |
| Rat | 0 | + | + | +++ ++ | + | ++ |
| Rabbit | + | ++ | ++ | +++ + | + | ++ |
| Monkey | + | + | + | +++ + | +++ | ++ |
| Dog | +++ | ++ | +++ | +++ | + | + |
| Human | +++ | ++ | ++ | +++ | + | + |