Compound | IC50 | ||
---|---|---|---|
Dextromethorphan | Midazolam | Testosterone | |
μM | |||
Ketoconazole | 0.28 | 0.07 | 0.03 |
3 | 2.16 | 5.43 | 4.54 |
4 | 1.00 | 2.29 | 2.70 |
5 | 0.93 | 6.78 | 6.16 |
10 | 1.13 | 4.91 | 6.76 |
12 | >30.00 | >30.00 | >30.00 |
15 | 3.36 | 8.58 | 15.90 |
18 | 0.54 | 1.86 | 0.69 |
22 | 11.40 | 31.6 | 13.80 |
23 | 0.68 | 1.87 | 2.05 |
25 | 1.03 | 3.76 | 5.40 |
26 | 0.99 | 9.98 | 1.89 |
28 | 31.9 | 40.4 | 26.30 |
39 | 2.47 | 10.6 | 6.49 |
44 | 0.81 | 1.34 | 0.85 |
45 | 16.90 | 35.00 | 4.68 |
52 | 37.50 | 66.40 | 11.20 |