Table 2b

Michaelis-Menten parameters for ester synthesis and hydrolysis obtained by model fitting

	Synthesis		Hydrolysis
	V_max		K_m
	nmol/h (CV%)		nM(CV%)
Trachea
	26 (108)^3-a
1^s ^tCompartment		328 (19)	30 (71)	230 (25)
	220 (24)^3-b
	0.26 (107)^3-a
2ⁿ ^dCompartment		0.021 (376)	2590 (109)	710 (408)
	0.60 (69)^3-b
	97 (12)^3-a
Lung		951 (81)	30 (71)	230 (25)
	280 (65)^3-b
Muscle	794 (92)	56 · 10³ (158)	30 (71)	230 (25)
Plasma	0.201 (64)	4.4 (32)	30 (71)	230 (25)

↵3-a Parameters obtained after intravenous administration.
↵3-b Parameters obtained after inhalation.