Kinetic parameters for inhibition of coumarin 7-hydroxylase activity of CYP2A6 by organosulfur compounds
| Chemicals | Ki | Type of Inhibition |
|---|---|---|
| μM | ||
| Di-n-propyl disulfide | 1.73 ± 0.12 | Competitive |
| Diallyl disulfide | 2.13 ± 0.25 | Mixed |
| 4,4′-Dipyridyl sulfide | 0.072 ± 0.016 | Competitive |
| 4,4′-Dipyridyl disulfide | 0.060 ± 0.014 | Competitive |
Values are presented as means ± S.D. (n = 3).