Table 5

Rate of depentylation of 100 μM MPN by microsomes from rat tissues

TissueMicrosomes/TubeNo. of TestsDepentylation Rate
μg protein pmol PENT/mg protein/min, mean ± S.E.
Esophagus50–1002414.5  ± 2.1
Forestomach50–10040.8  ± 0.3
Glandular stomach10040.4  ± 0.1
Small intestine50–10040
Large intestine10062.7  ± 0.6
Liver1001024.9  ± 4.5
Kidney50–10040.1  ± 0
Lung50–10047.0  ± 1.1

Results were obtained with four preparations of esophageal microsomes and one preparation each of microsomes from the other listed tissues. Each microsomal preparation was isolated from the tissues of at least two rats.