Table 1

Material balance in male and female rats at sacrifice (96 h) after a single oral dose of [¹⁴C]TY029

Sample	Percentage of Dose
	High Dose		Low Dose
	Male		Female		Male		Female
	Mean	S.D.	Mean	S.D.	Mean	S.D.	Mean	S.D.
Cage wash	0.93	0.26	3.67	1.70	1.29	0.67	2.22	1.18
Residual feed	0.66	0.28	2.56	3.39	1.06	0.33	0.73	0.69
Urine	31.67	14.24	69.21	8.58	37.39	4.62	65.45	6.11
Feces	57.47	12.24	26.09	4.53	47.15	2.09	16.11	1.22
Tissues	0.26	0.14	0.06	0.05	0.22	0.10	0.28	0.22
Total excretion	89.15	2.86	95.30	10.79	84.54	2.92	81.56	7.29
Material balance	90.65	3.17	101.63	9.66	86.84	2.69	84.80	6.97