Table 3

Calculation of scaling factors for compound A

Organ Weight (A)3-aSlice Weight (B)Fraction Metabolized (C)3-b(A/B) · CScaling Factor
g mg
Liver15.3140.212300.38
Lung6.930<0.0100
Kidney2.9140.0714.50.02
Small intestine7.220.103600.60

  • ↵3-a  Derived from de Kanter et al. (2002).

  • ↵3-b  Data from Table 2.