Table 1

Structures and modulatory effects of sixteen compounds on 3-glucuronidation of 5 μM estradiol

CompoundMolecular StructureModulator range, μMStimulation/inhibition (5 μM estradiol)IC50

IC50 values are given where appropriate and are based on the effects of four concentrations of modulator. n/p, not performed due to technical difficulties with the assay.