Excretion of radioactivity in urine and feces from male-F344 rats (n = 4) following an oral 30-mg/kg dose of [14C]LY354740 monohydrate
| Dosing Route | Time | Dose Recovered (Mean ± S.E.M.) | |
|---|---|---|---|
| Urine | Feces | ||
| h | % | ||
| p.o. | 0–24 | 14.27 ± 1.29 | 83.67 ± 1.24 |
| 24–48 | 0.35 ± 0.03 | 3.33 ± 0.53 | |
| 48–72 | 0.12 ± 0.04 | 0.27 ± 0.06 | |
| 72–96 | 0.05 ± 0.01 | 0.07 ± 0.05 | |
| Total | 14.79 ± 5.08 | 87.34 ± 5.71 | |
| Total recovery7-a | 103.54 ± 3.37 | ||
↵7-a Total recovery includes carcass and cagewash.