Sample | High Dose | Low Dose | ||||||
---|---|---|---|---|---|---|---|---|
Male3-a | Female | Male | Female | |||||
Mean | S.D. | Mean | S.D. | Mean | S.D. | Mean | S.D. | |
% of dose | ||||||||
Carcass | 11.08 | 2.42 | 4.85 | 1.75 | 6.15 | 2.35 | 4.85 | 2.33 |
Skin | 0.14 | 0.04 | 0.06 | 0.02 | 0.10 | 0.02 | 0.07 | 0.02 |
Whole blood | 2.48 | 0.57 | 0.79 | 0.33 | 1.61 | 0.57 | 1.16 | 0.83 |
Bone marrow | <LOD | <LOD | <LOD | <LOD | ||||
Brain | 0.02 | 0.02 | 0.02 | 0.02 | ||||
Fat | 0.06 | 0.02 | 0.12 | 0.16 | 0.03 | 0.04 | 0.02 | |
RBC | 0.21 | 0.09 | 0.07 | 0.05 | 0.14 | 0.04 | 0.08 | 0.05 |
Heart | 0.11 | 0.04 | 0.04 | 0.02 | 0.08 | 0.03 | 0.08 | 0.04 |
Lungs | 0.19 | 0.08 | 0.08 | 0.02 | 0.20 | 0.08 | 0.14 | 0.07 |
Spleen | 0.03 | 0.01 | 0.02 | 0.02 | ||||
Liver | 6.14 | 1.85 | 4.22 | 0.96 | 40.22 | 2.90 | 20.13 | 4.24 |
Kidney | 1.07 | 0.48 | 1.14 | 0.89 | 1.09 | 0.36 | 0.86 | 0.34 |
GI tract | 3.80 | 2.11 | 2.06 | 0.24 | 2.51 | 0.42 | 3.49 | 2.12 |
GI contents | 46.32 | 11.45 | 34.51 | 8.92 | 39.32 | 11.27 | 15.9 | 6.57 |
Pituitary | 0.01 | <LOD | <LOD | <LOD | ||||
Thyroid | <LOD | <LOD | <LOD | <LOD | ||||
Testes | 0.23 | 0.07 | <LOD | 0.11 | 0.03 | <LOD | ||
Ovaries | <LOD | 0.01 | <LOD | 0.01 | ||||
Pancreas | 0.03 | 0.02 | 0.03 | 0.04 | 0.01 | 0.03 | 0.02 | |
Adrenals | 0.01 | <LOD | 0.01 | 0.01 | ||||
Plasma | 0.52 | 0.17 | 0.27 | 0.19 | 0.43 | 0.10 | 0.28 | 0.15 |
Uterus | <LOD | 0.04 | 0.02 | <LOD | 0.03 | 0.02 | ||
Muscle | 0.16 | 0.07 | 0.07 | 0.02 | 0.10 | 0.04 | 0.08 | 0.04 |
Bone | 0.02 | 0.01 | 0.02 | 0.01 | ||||
Subtotal | 72.64 | 48.35 | 92.16 | 47.26 |
RBC, red blood cell.
↵3-a Mean for three male rats because one animal in this group was miss-dosed. The data from this animal were eliminated.