Table 1
Metabolism of NO-1886 in human liver S9 and microsomes in the presence and absence of NADPH
Metabolism Rate
M-2
M-3
pmol/min/mg protein
Microsomes
NADPH(
+
)
118.31
NADPH(−)
9.77
S9
NADPH(
+
)
7.91
0.45
NADPH(−)
0.02
0.59