Table 3

Effective (P*eff) and wall permeability (P*w) of genistein and analogs before (calculated) and after correction (corrected) for the excretion of phase II metabolites

P*effP*w
CalculatedCorrectedCalculatedCorrected
Genistein2.99  ± 0.611.62  ± 0.43>7>7
Apigenin4.41  ± 0.522.02  ± 0.77>7>7
Genistin1.85  ± 0.260.62  ± 0.38>71.16  ± 0.87
Apigetrin6.17  ± 0.530.49  ± 0.18>70.72  ± 0.36