Kinetic parameter estimates for 4′-hydroxylation of (S)-flurbiprofen by the CYP2C9 variants
Values are the parameter estimates ± S.E. of the estimate.
↵1-a Fitted to the standard Michaelis-Menten equation (model 1).
↵1-b CLint calculated as the ratio of Vmax/Km, a measure of the efficiency of the enzyme.