Table 3

Quantitative analysis of the levels of CYP2A3 mRNA in 2-month-old transgenic mice

Line No.Levels of CYP2A3 mRNA
BrainKidneyLiverLungOlfactory BulbOlfactory Mucosa
attomol/mg RNA
14823-a 116  ± 2315  ± 50.1  ± 0.1N.D.10  ± 5
26993-a 10  ± 17  ± 112  ± 111  ± 1
27013-b 39  ± 619  ± 14
27143-c 0.5 (0.4, 0.5)2.9 (2.9, 2.8)1.7 (1.8, 1.6)0.9 (0.7, 1.0)0.9 (0.9, 0.9)1.5 (0.9, 2.1)
  • —, not detected; N.D., not determined.

  • 3-a  Three individual male mice were analyzed and results are presented as means ± S.D.

  • 3-b  Four groups of mice (two male and two female groups; each group has three mice, and the tissues were pooled within a group) were analyzed, and the results are presented as means ± S.D.

  • 3-c  Two groups of mice (one male group and one female group; each group has three mice, and the tissues were pooled within a group) were analyzed, and the results are presented as the average of male and female groups. Values for each group are presented in parentheses (male, female).