Metabolite Code | Rats | Dogs | |
---|---|---|---|
Male | Female | ||
0–48 h | 0–48 h | ||
UD | 5.6 | 12.3 | 1.1 |
6 | 1.6 | 0.4 | 1.3 |
8 | 0.9 | 0.4 | 1.2 |
10 | 0.2 | 0.5 | — |
13 | — | 0.2 | — |
14 | 0.4 | — | 0.1 |
15 | 1.3 | 8.5 | — |
16 | 0.4 | 0.2 | — |
18 | 5.7 | 1.6 | — |
19 | 1.7 | 0.3 | — |
20 | 5.1 | 1.1 | — |
21 | 2.4 | 0.1 | — |
22 | — | 0.6 | — |
Sum | 25.3 | 26.2 | 3.7 |
Figures represent the percentage of the dose radioactivity.
—, not detected or below the limit of quantification.