Inducer | Concentration | References | Glucuronidation | Sulfation |
---|---|---|---|---|
μM | % of control | |||
t-Butylhydroquinone | 50 | Münzel et al. (1999) | 122 ± 24 | 117 ± 9 |
Dexamethasone | 1 | Doostdar et al. (1993), | 88 ± 4 | 91 ± 6 |
Donato et al. (1995) | ||||
3-Methylcholanthrene | 1 | Donato et al. (1995), | 200 ± 403-a | 116 ± 2 |
Chung and Bresnick (1994), | ||||
Ritter et al. (1999), | ||||
Runge et al. (2000) | ||||
β-Naphthoflavone | 50 | Runge et al. (2000), | 96 ± 10 | 97 ± 8 |
Abid et al. (1995) | ||||
Oltipraz | 50 | Ritter et al. 1999 | 187 ± 183-a | 82 ± 6 |
Phenobarbital | 2000 | Doostdar et al. (1993), | 98 ± 9 | 69 ± 5 |
Donato et al. (1995), | ||||
Ritter et al. (1999), | ||||
Runge et al. (2000) | ||||
TCDD | 0.01 | Bock et al. (1999), | 99 ± 17 | 99 ± 7 |
Münzel et al. (1999) |
The cells were treated for 1 (TCDD) or 3 days with vehicle or potential inducer and the formation of chrysin glucuronide and sulfate was measured by HPLC in the medium after a 6-h incubation of the cells with chrysin.
↵3-a Significantly higher than control; P < 0.05.