↵2-a  Values, expressed as picomole product per minute per picomole enzyme, represent the mean of duplicate determinations. Ranges were on average <10% of the mean. Bold values indicate the highest catalytic activity within the panel.

↵2-b  Dashes indicate activity was below the limit of detection which was considered as that corresponding to a signal to background ratio of approximately 1.5. These values and their substrates were 0.05 min⁻¹, AMMC; 0.05 min⁻¹, BFC; 0.008 min⁻¹, CMC; 0.008 min⁻¹, CEC; 0.003 min⁻¹, DBF; 0.05 min⁻¹, MFC; 1.0 min⁻¹, BQ; and 0.008 min⁻¹, BzRes.

↵2-c  Microsomes from human lymphoblastoid cells engineered to express the rat enzyme.

↵2-d  Concentration for all enzymes was 50 nM except for CYP2A1 (20 nM) and for CYP2E1 (87 nM).

↵2-e  Concentration for all enzymes was 50 nM except for CYP1A1, which was 2.5 nM.