Enzyme kinetic analyses of the formation of N-desmethyl LY333531 by human liver microsomes
| Sample | KM | Vmax | Clint (Vmax/KM) |
|---|---|---|---|
| μM | pmol/min/mg | μl/min/mg | |
| Human Liver Microsomes | |||
| HLB | 1.0 ± 0.11-a | 533 ± 30 | 533 |
| HLG | 3.2 ± 0.3 | 1033 ± 64 | 323 |
| HLQ | 1.1 ± 0.1 | 491 ± 26 | 446 |
↵1-a Parameter estimate ± standard error of the parameter estimate.