Results of screening assays with expressed human UDP-glucuronosyltransferases.
| UGT Isoform | α-DHA-G Formation | Control Substrate | Control Activity |
|---|---|---|---|
| pmol min−1 mg−1 | nmol min−1 mg−1 | ||
| UGT1A1 | Octylgallate | 1.1 | |
| UGT1A6 | 1-Naphthol | 3.2 | |
| UGT1A9 | 8.4 | Propofol | 1.2 |
| UGT2B7 | 11.8 | Hyodeoxycholic acid | 0.75 |
Control activities indicate the activity of the expressed UGT preparation with an ideal substrate using a radiochemical HPLC assay.