Table 2

Results of screening assays with expressed human UDP-glucuronosyltransferases.

UGT Isoformα-DHA-G FormationControl SubstrateControl Activity
pmol min−1 mg−1 nmol min−1 mg−1
UGT1A1Octylgallate1.1
UGT1A61-Naphthol3.2
UGT1A98.4Propofol1.2
UGT2B711.8Hyodeoxycholic acid0.75

Control activities indicate the activity of the expressed UGT preparation with an ideal substrate using a radiochemical HPLC assay.