Changes in tissue (+)-AMP to (+)-METH AUC molar ratios in control and mAb-treated rats.
↵ a The molar ratio of (+)-AMP to (+)-METH AUC was calculated by dividing the nmol · h/g or nmol · h/ml AUC04.5h values.
↵ b Control rats were treated with vehicle 17 h before a 1 mg/kg i.v. (+)-METH dose.
↵ c Rats were treated with anti-(+)-METH mAb6H4 17 h before a 1 mg/kg i.v. (+)-METH dose.