M3 | M5 | M8 | ||
---|---|---|---|---|
w/o GSH | w GSH | |||
K m 1-150 | 1.9 ± 0.6 | 65.8 ± 6.6 | 15.1 ± 2.7 | 15.6 ± 2.2 |
V max | 10.2 ± 1.5 | 25.6 ± 2.7 | 22.9 ± 2.3 | 23.2 ± 0.7 |
Clint | 0.005 | 0.39 | 1.52 | 1.49 |
↵1-150 Km values in millimolar forM3 and in micromolar for M5 and M8;Vmax is in picomoles of metabolite produced per minute per milligram of protein; Clint (intrinsic clearance = Vmax/Km) values are given as microliters per minute per milligram of protein (×103).