Preparation | ApparentKm | Vmax |
---|---|---|
mM | nmol/min/mg | |
LV3 | 6.7 ± 0.2 | 4.3 ± 0.00 |
LV19 | 6.8 ± 0.4 | 0.62 ± 0.01 |
LV22 | 5.2 ± 0.3 | 6.8 ± 0.1 |
LV35 | 8.8 ± 0.3 | 43.4 ± 0.4 |
LV39 | 5.7 ± 1.3 | 17.6 ± 1.1 |
LV41 | 6.1 ± 0.8 | 51.3 ± 2.1 |
LV49 | 6.2 ± 0.5 | 24.4 ± 0.6 |
Pooled kidney | 6.5 ± 0.9 | 8.8 ± 0.4 |
Pooled lung | 4.9 ± 3.3 | 0.03 ± 00 |
Pooled intestine | 12.4 ± 2.0 | 0.22 ± 00 |
UGT1A6(B) | 5.0 ± 0.4 | 4.5 ± 0.1 |
UGT1A6(L) | 5.9 ± 0.2 | 15.8 ± 0.2 |
Data were fitted by nonlinear regression to the Michaelis-Menten equation. Shown are parameter estimates ± S.E. of the estimates.