Dose | Bisphenol A Disappearance (nmol/10-cm bowel/60 min) | ||||
---|---|---|---|---|---|
I | II | III | IV | Colon | |
μM | |||||
10 | 175 ± 22 | 158 ± 14 | 163 ± 14 | 198 ± 18 | 244 ± 7 |
50 | 751 ± 92 | 996 ± 98 | 862 ± 111 | 1086 ± 105 | 1163 ± 98 |
100 | 1325 ± 324 | 1581 ± 282 | 1556 ± 143 | 1592 ± 220 | 2016 ± 114 |
Bisphenol A was added to the mucosal buffer solution of each segment in concentrations of 10 μM, 50 μM, and 100 μM. The amount of bisphenol A disappearance (mean ± S.E.) was obtained by subtracting the final amounts of bisphenol A in the mucosal buffer solution after 60-min incubation. I, II, III, and IV indicate the intestinal sites in distal order from the ligament of Trietz.