Table 4

Mean (± S.D.) Emax and EC50 for urine flow rate and urinary excretion rates of sodium, potassium, and chloride in control rats and mutant Nagase analbuminemic rats (NARs)

ParametersEmaxEC50
Control RatsNARsControl RatsNARs
ml/min/kg or mmol/min/kg μg/min/kg
Urine flow rate2.42  ± 0.9223.00  ± 0.7369.83  ± 6.873.45  ± 2.014-a
Urinary excretion rate of sodium0.283  ± 0.1000.420  ± 0.1064-a 8.02  ± 4.284.06  ± 1.974-a
Urinary excretion rate of chloride0.352  ± 0.1110.478  ± 0.1014-a 9.59  ± 4.965.00  ± 2.404-a
Urinary excretion rate of potassium0.0493  ± 0.02790.0367  ± 0.0083426.6  ± 15.38.83  ± 8.404-a
  • 4-ap < 0.05.