Metabolites | |||||||
---|---|---|---|---|---|---|---|
M6 | M7 | M13 | M14 | M18 | M19 | Traxoprodil | |
EM4-a | |||||||
2 | 1.4 ± 0.3 | 10.5 ± 1.8 | 5.3 ± 0.9 | 32.8 ± 5.0 | nd | nd | 38.3 ± 8.1 |
6 | 5.0 ± 1.2 | 27.9 ± 2.7 | 5.2 ± 0.6 | 36.4 ± 3.3 | nd | nd | 12.9 ± 2.6 |
24 | 4.8 ± 2.8 | 13.8 ± 1.3 | 4.8 ± 0.9 | 26.2 ± 11.0 | nd | nd | 12.5 ± 13.2 |
PM4-b | |||||||
2 | 6.2, 6.7 | nd | nd | nd | 1.1, 0.8 | 4.7, 5.2 | 79.1, 77.6 |
6 | 34.7, 34.7 | nd | nd | nd | 1.9, 2.1 | 4.2, 4.0 | 55.4, 50.7 |
24 | 38.8, 35.6 | nd | nd | nd | 4.4, 2.6 | 4.0, 4.4 | 43.7, 46.2 |