Sample | Interval | Percent of Dose Recovered2-a | |||
---|---|---|---|---|---|
Oral | i.v. | ||||
Mean | S.D. | Mean | S.D. | ||
h | |||||
Urine | 0–2 | 2.96 | 0.98 | 2.40 | 1.03 |
2–4 | 6.33 | 1.48 | 5.11 | 3.47 | |
4–6 | 3.62 | 1.51 | 5.71 | 2.92 | |
6–9 | 5.53 | 2.09 | 4.78 | 1.64 | |
9–12 | 5.39 | 1.99 | 7.91 | 2.44 | |
12–18 | 3.85 | 2.27 | 4.59 | 3.22 | |
18–24 | 5.62 | 4.54 | 4.35 | 1.86 | |
24–36 | 7.83 | 1.23 | 11.20 | 4.66 | |
36–48 | 5.14 | 1.35 | 7.23 | 3.31 | |
48–72 | 5.83 | 1.42 | 8.19 | 3.13 | |
72–96 | 4.16 | 1.24 | 3.58 | 1.87 | |
96–120 | 2.17 | 1.66 | 2.70 | 1.57 | |
120–168 | 1.58 | 2.04 | 2.34 | 2.47 | |
Sub Total | 60.0 | 5.50 | 70.1 | 12.1 | |
Feces | 0–24 | 2.17 | 2.04 | 1.00 | 1.63 |
24–48 | 3.92 | 2.64 | 5.40 | 4.42 | |
48–72 | 7.48 | 4.62 | 6.84 | 3.81 | |
72–96 | 2.55 | 2.18 | 3.31 | 2.62 | |
96–120 | 1.82 | 1.55 | 1.53 | 1.59 | |
120–144 | 0.79 | 0.75 | 1.83 | 2.27 | |
144–168 | 0.71 | 0.83 | 0.73 | 0.53 | |
168–192 | 0.56 | 0.93 | 0.33 | 0.34 | |
192–216 | 0.13 | 0.23 | 0.07 | 0.06 | |
216–240 | 0.15 | 0.21 | 0.25 | 0.53 | |
Sub Total | 20.3 | 7.84 | 20.4 | 6.59 | |
Urine and Feces | Total | 80.3 | 7.10 | 90.4 | 13.3 |
↵2-a Data represent mean and S.D. (n = 6 subjects).