Correlation between the formation of amprenavir metabolites and CYP3A content in microsomes from neonates, infants, and adults (n = 12)
| M2 | M3 | M4 | M5 | CYP3A | |
|---|---|---|---|---|---|
| M1 | 0.68 | 0.36 | 0.64 | 0.56 | 0.51 |
| M2 | 1 | 0.83 | 0.59 | 0.97 | 0.66 |
| M3 | 1 | 0.07 | 0.82 | 0.41 | |
| M4 | 1 | 0.58 | 0.62 | ||
| M5 | 1 | 0.70 |