Table 2

Renal and non-renal clearance and fraction of drug excreted unchanged in urine following a single oral dose (1 mg) of [14C3]moxonidine to healthy male subjects

Subject No.CLRCLNRfeur0–12 h
l/h l/h % of dose
129.812.968.8
224.07.576.7
34.6211.846.5
430.19.8877.0
  • CLR , renal clearance; CLNR , non-renal clearance; feur , fraction of drug excreted in urine.