Table 3

Proteins identified by peptide mass fingerprinting in PB-induced rabbit liver microsomes.

ProteinSWISS-PROT Accession NumberpIMolecular Weight PB-Induced Microsomes, 1DE SeparationPB-Induced Microsomes, LC-Separation
Number of Matched PeptidesSequence CoverageNumber of Matched PeptidesSequence Coverage
kDa %%
UDP-Glucuronosyltransferase B13 P36512 8.860.53918818
Cytochrome P450 1A1 P05176 9.758.328161023
Cytochrome P450 1A2 P05176 8.858.267151125
Cytochrome P450 2A10 Q05555 9.357.1710201223
Cytochrome P450 2B43-150 P00178 9.355.7314321233
Cytochrome P450 2C1 P00180 9.054.591121
Cytochrome P450 2C14 P17666 9.055.701119
Cytochrome P450 4B1 P15128 9.058.608151021
Epoxide hydrolase P04068 7.352.492246
  • 3-150 Traces of CYP2B5 (only one of seven isozyme-specific tryptic peptides was found, at the same time five out of six isozyme-specific tryptic peptides for CYP2B4 were found)