Table 2

Parameter estimates from simultaneous fitting of mean outflow IDOL data after 10-min infusion of IDA in hearts of control, verapamil-(1 nM), and amiodarone- (1 μM) treated groups

Parameter	Estimate^2-a	FSD^2-b
k _m,1 (min⁻¹)	0.0023	0.08
k _m,2 (min⁻¹)	0.0081	0.08
V _max,IDOL (nmol/min)	242	0.15
K _M,IDOL (nmol)	185	0.17
k _21,IDOL (min⁻¹)	0.047	0.14
k _23,IDOL (min⁻¹)	0.041	0.04
V ₁ ^2-c (ml)	14
fV _{max,IDOL,verapamil}	1.64	0.03
fk _{23,IDOL,verapamil}	1.26	0.04
fV _{max,IDOL,amiodarone}	1.22	0.05
fk _{23,IDOL,amiodarone}	1.13	0.04

The corresponding IDA data have been published previously (Weiss and Kang, 2002).

↵2-a Final estimates with fixed parameters of IDA taken from the previous publication (Weiss and Kang, 2002).
↵2-b Fractional standard deviations.
↵2-c Fixed to the initial distribution of IDA.