TABLE 2

The RBC/plasma, liver/plasma and intestine/plasma ratios of AUC(15-45) values obtained for the combined concentration of all metabolites after treatment of mice with 42.5 μmol/kg cis-AVTP, trans-AVTG, or 6-TG as described under Materials and Methods.

Values presented are the means ± S.D. from three-independent experiments.




RBC/Plasma

Liver/Plasma

Intestine/Plasma
cis-AVTP 0.4 ± 0.1* 2.5 ± 1.2* 4.0 ± 1.1*
trans-AVTG 1.0 ± 0.1 8.5 ± 1.2 8.4 ± 0.3
6-TG
1.2 ± 0.2
4.4 ± 0.6*
6.2 ± 1.8
  • * Significantly different from the ratio obtained after treatment with trans-AVTG (P < 0.05)