TABLE 2

Allelic frequency of common FMO3 polymorphisms in non-Hispanic African-American and non-Hispanic Caucasian populations

Population
Number of individuals
H132 (C→G)
K158 (A→G)
M257 (A→G)
G308 (G→A)
P360 (C→T)
African American
    Mississippi 16 0.063 0.563 0.000 0.094 0.000
    South Carolina 63 0.024 0.492 0.008 0.041 0.026
    City of Hopea 50 0.020 0.480 0.005 N.D. 0.020
    HBRI 5 0.000 0.700 0.010 0.010 0.000
    Total alleles 268 7 135 7 9 5
    Frequencyb 0.026 0.50 0.026 0.056 0.019
Caucasian
    Coriell 92 0.000 0.540 0.280 0.226 0.000
    HBRI 28 0.000 0.520 0.036 0.214 0.000
    Total alleles 240 0 128 53 53 0
    Frequencyc
0.00*
0.53
0.22**
0.22**
0.00

  • N.D., not determined.

  • ↵* p < 0.05; ** p < 0.001, African-American versus Caucasian populations.

  • ↵ a Previously described by Furnes et al. (2003).

  • ↵ b Total allelic frequency observed for 268 alleles.

  • ↵ c Total allelic frequency observed for 240 alleles.