Descriptive information for human liver donors
HL Microsomes | |||
|---|---|---|---|
| CYP3A4 | CYP3A4/5 | ||
| (n = 18) | (n = 14) | ||
| Sex | 8 M/10 F | 9 M/5 F | |
| Age (yr) | 36 ± 17 | 47 ± 16 | |
| CYP3A4 content (pmol/mg) | 92 ± 66 | 70 ± 50 | |
| CYP3A5 content (pmol/mg) | 3.1 ± 1.5* | 93 ± 69 | |
| Percentage CYP3A5 of total CYP3A (%) | 4.1 ± 2.0* | 60 ± 13 | |
M, male; F, female.
↵* Significant difference by unpaired t test (p < 0.05).