Enzyme | Number of Compounds | Number of Compounds per Km | ||||
---|---|---|---|---|---|---|
Km <10 μM | Km = 10-100 μM | Km >100 μM | ||||
CYP1A1 | 12 | 7 | 4 | 1 | ||
CYP1A2 | 43 | 17 | 16 | 10 | ||
CYP2A6 | 15 | 1 | 3 | 11 | ||
CYP2B6 | 51 | 15 | 19 | 17 | ||
CYP2C8 | 13 | 6 | 5 | 2 | ||
CYP2C9 | 41 | 12 | 21 | 8 | ||
CYP2C19 | 48 | 18 | 21 | 9 | ||
CYP2D6 | 75 | 45 | 23 | 7 | ||
CYP2E1 | 19 | 2 | 8 | 9 | ||
CYP3A4 | 126 | 38 | 56 | 32 | ||
CYP3A5 | 12 | 5 | 6 | 1 | ||
CYP19 | 18 | 18 | 0 | 0 | ||
Total | 491 | 180 | 208 | 103 |