TABLE 3

Concentration of radioactivity (nanocuries per gram) in tissues of four Sprague-Dawley male rats at 15 min after a single intravenous bolus dose of [3H]glucose

Mean radioactivity values were calculated by averaging 1) tissue concentrations measured at different sectioning levels and/or 2) tissue concentrations measured from replicate cryosections obtained from the same sectioning level; n values range from a minimum of 3 to a maximum of 12.


Tissue

275 μCi/kg

865 μCi/kg

2360 μCi/kg

4320 μCi/kg
Adipose, brown 436 ND 1680
Adipose, white 301 ND 451
Blood, myocardium 144 622 1590 2640
Blood, systemic 162 554 1580 2500
Bone marrow 288 642 1050
Cerebellum 149 515 1470 1950
Cerebrum 154 525 1320 2400
Eye 404 1830 6530 8650
Harderian gland 241 842 ND 2350
Heart 315 1040 1290
Intestinal mucosa 352 1260 3120 5550
Kidney 463 1230 1790
Liver 151 533 1550 2040
Lung 171 560 1670 1820
Medulla oblongata 172 621 1700 1930
Muscle 195 188
Pancreas 183 521 544
Salivary gland 216 747 872
Skin 455 1140 1970
Spinal cord 135 551 1440 1580
Spleen 240 579 787
Thymus

245
587
767
  • —, below lower quantification limit of 127 nCi/g; ND, tissue concentration not determined.