TABLE 2

Effects of CMPF and indoxyl sulfate on the microsomal metabolism of Ery

Concentrations
N-Demethyl-Erya
CMPF
Indoxyl Sulfate
μM % of control
0 100.0 ± 2.4 100.0 ± 5.5
25 99.2 ± 1.0 99.7 ± 2.8
50 99.0 ± 1.2 91.8 ± 2.8
100 92.0 ± 3.1 79.3 ± 4.6b
200 85.1 ± 3.7b 81.2 ± 6.8b
400 80.5 ± 3.1b 76.3 ± 2.7b
800
72.6 ± 5.1b
69.1 ± 4.6b

  • ↵ a Each value represents mean ± S.E.M.

  • ↵ b p < 0.05, significantly different from control