TABLE 2

PXR response elements in CYP2B6, CYP3A4, CYP3A7, and MDR1

Element	Configuration	Sequence	Reference
CYP2B6	DR4	GGGTCAggaaAGTACA	Goodwin et al., 2001
CYP3A4-P	ER6	TGAACTcaaaggAGGTCA	Goodwin et al., 1999
CYP3A4-D	DR3	TGAACTtgcTGACCC	Goodwin et al., 1999
CYP3A7-P	ER6	TTAACTcaatggAGGTCA	Pascussi et al., 1999
CYP3A7-D	DR3	TGAACTtgcTGACCC	Bertilsson et al., 2001
MDR1	DR4	TGAACTaactTGACCT	Geick et al., 2002