Inhibition of aldehyde oxidase-catalyzed reactions by raloxifene
Values represent the mean (±standard error) of triplicate determinations.
Reaction | Model | Ki | r2 |
|---|---|---|---|
| nM | |||
| Phthalazine → 1-phthalazinone | Uncompetitive | 0.87 (±0.05) | 0.998 |
| Vanillin → vanillic acid | Uncompetitive | 1.2 (±0.1) | 0.982 |
| Nicotine-Δ1′(5′)-iminium ion → cotinine | Uncompetitive | 1.4 (±0.1) | 0.982 |
| CP-544,439 → deoxyCP-544,439 | Noncompetitive | 51 (±3) | 0.995 |