TABLE 5

The median GI50, TGI, and LC50 values obtained for cis-AVTP, trans-AVTG, 6-MP, and 6-TG in the NCI anticancer screen All values are in micromolar concentration (μM).


Parameter

cis-AVTP

trans-AVTG

6-MP

6-TG
GI50 0.60 0.98 4.02 1.08
TGI 4.56 12.9 >100 44.8
LC50
38.6
76.2
>100
>100