Comparison of nucleotide sequences recognized by PXR and hormonal receptors (VDR, TR, and RAR)
Motif | Consensus Sequence | Receptor | ||
|---|---|---|---|---|
| PXR Response Element | Hormonal Receptor Response Element | |||
| DR3 | AG (G/T) TCA NNN AG (G/T) TCA | (G/A) GGT (C/G) A NNN (G/A) GGT (C/G) A | VDR | |
| DR4 | AG (G/T) TCA NNNN AG (G/T) TCA | (G/A) GGT (C/G) A NNNN (G/A) GGT (C/G) A | TR | |
| DR5 | AG (G/T) TCA NNNNN AG (G/T) TCA | (G/A) GGT (C/G) A NNNNN (G/A) GGT (C/G) A | RAR | |