Total P450 Contents | Activities | |||||
---|---|---|---|---|---|---|
p-Hydroxylation | 3-Hydroxylation | N-Desmethylation | ||||
nmol/mg protein | pmol/min/mg protein | |||||
SD | 0.80 ± 0.08 | 172 ± 3.0** | 146 ± 26.1 | 27.5 ± 0.9 | ||
BN | 0.73 ± 0.05 | 156 ± 8.3** | 116 ± 8.3 | 31.3 ± 1.0 | ||
DA | 0.83 ± 0.03 | 0.4 ± 0.0 | 457 ± 35.7** | 67.3 ± 1.8** | ||
W | 0.73 ± 0.08 | 0.5 ± 0.0 | 141 ± 19.3 | 24.8 ± 1.6 |
↵** Significant difference from W rats (p < 0.01).