TABLE 5

Ionspray mass spectral data of CP-424391 metabolites in rats


Metabolite

Retention Time

[M + H]+

CID Mass Spectral Data
min m/z (% abundance)
CP-424391 13.0 506 421(10), 263(8;), 244(100), 235(17), 215(8), 91(3)
M1 3.5 402 317(10), 230(100), 173(20)
M2 5.8 416 331(5), 244(100), 215(60)
M3 7.9 508 402(100), 230(60), 173(40)
M4 8.5 538 331(10), 244(100), 173(10), 123(5)
M5 9.9 522 416(5), 279(5), 244(100), 107(10)
M6 10.2 552 331(15), 244(100), 215(8), 173(10), 137(25)
M7 11.3 492 407(5), 235(15), 230(100), 91(3)
M8
11.8
432
418(100), 331(15), 244(75)