TABLE 1

Alkaline and enzymatic hydrolysis of the glucuronide and glucoside conjugates of mycophenolic acid produced in vitro

Results are presented as the mean percentage of hydrolysis with respect to controls (duplicate experiments).




Alkaline

β-Glucuronidase

β-Glucosidase
%
MPAG 5 99 NT
AcMPAG 91 3 NT
MPAGls 16 NT 99
AcMPAGls
87
NT
13
  • NT, not tested.